Clinical Trials

Dental student sitting and chatting with a trial patient

What Is Clinical Research?

Clinical research looks for better ways to treat, prevent, diagnose, and understand human disease. Only through clinical research can we gain insights and answers about the safety and effectiveness of new drugs and medical devices, or new ways to use them. 

The volunteers who participate in clinical research make it possible for this to occur. A clinical trial may offer you or your family member experimental treatment for a disease. Many of our studies also involve healthy patients.  

TUSDM’s research efforts are directed towards promoting oral health and sharing our resources and ideas to improve the quality of life of the general population.

Click here for more information about Clinical Trials.

What are my rights as a research participant?

As a participant in a research study/clinical trial, you have the right:

  • To be told why the study is being conducted.
  • To be told who is funding the study.
  • To be given an explanation of what will happen during the study, what is expected of you, and what will be different from non-research medical treatment.
  • To be given an explanation of risks or discomforts that may be experienced from participating in the study.
  • To be given an explanation of any benefits that may be expected from participating in the study.
  • To be told, if treatment is part of the study, of other non-research treatment choices that are available and how they compare to participating in the study.
  • To be given the opportunity to ask questions about the study or participating in the study before agreeing to participate and during the course of the study.
  • To be told of your right to refuse to begin the study, or to change your mind and stop participating in the study after it has started. Your participation is completely voluntary.  If treatment is part of the study, this decision will not affect your ability to receive non-research treatment.
  • To be told that you may refuse to answer any question.
  • To have enough time to decide whether or not to participate and to make that decision without any pressure from the people who are doing the research.
  • To be told, if treatment is part of the study, whether there are any costs to you associated with being in the study and whether you will receive any reimbursement for participating in the study.
  • To be told who will have access to information collected about you, how the information will be used, and how the confidentiality of your information will be protected.
  • To be told who to contact directly with questions about the research, about research related injury, and about your rights as a research participant.
  • To be told, if the research is greater than minimal risk, whether any compensation and medical treatments are available should you have a research related injury, what the treatments are, and where further information may be obtained.
  • To be told about new information learned during the study that might affect your safety or you willingness to continue to take part in the study.
  • To receive a copy of the consent form if one is part of the study.

Finding a Research Study

Our currently enrolling studies are listed below. Click on the title to see more details about the study and who can be enrolled.

If you don’t see a study you are interested in but would like to be contacted if we have a future study you may be eligible for, please complete our Research Volunteer Form.

Clinical Trials Currently Enrolling

  • Attention parents of kids ages 10-14: 

    If your child has had a cavity or a filling, and does not have braces, call us to see if your child qualifies for a toothpaste study with Colgate! 

    Contact: 617-636-2408 

    • Qualifying participants will receive $400 in Target gift cards for completing all 5 visits. 
    • Qualifying transportation costs will be covered 
    • Multiple study sites (Lawrence, Boston) for your convenience 
    • Evening and Saturday appointments available 

    PI: Dr. Andrea Zandona 

  • Description: The Periodontology Department of Tufts University School of Dental Medicine is conducting research on the systemic immune response in subjects with and without periodontitis.

    We are seeking volunteers who are between 40–70 years old and speak English and who have not received periodontal treatment in the past 3 months. Participants must be willing to attend 1–2 visits for this study (1 visit for patients without periodontitis and 2 visits for patients with periodontitis, 1 pre- and 1 post-treatment).

    Subjects participating in the study will receive a $25 gift card to CVS after each completed study visit (1 visit for healthy volunteers, 2 visits for patients with periodontitis).

    If you have any questions or if you think you may qualify to participate, please contact:

    Dr. Evangelos Papathanasiou
    Phone: 617-636-3887
    Email: evangelos.papathanasiou@tufts.edu

  • Efficacy of Arnica Montana in Reducing Post-Operative Swelling and Pain Following Third Molar Extraction

    Are you in need of a third molar extraction? The Oral & Maxillofacial Surgery Department is conducting research regarding the reduction of swelling and pain in impacted teeth.

    • Are you 18–40 years old?
    • Do you have at least 2 full or partially bony impacted third molar teeth?
    • Are you scheduled to have your extractions performed under anesthesia?
    • Are you able to follow directions and tolerate surgical procedures?

    If you complete all visits, you will receive $175 in Visa gift cards for your participation.

    If you have any questions or if you think you may qualify to participate, please contact:

    Dental Research Administration
    dentalresearchadministration@tufts.edu

  • The Oral Medicine Department at Tufts University School of Dental Medicine is doing research on the impact of a teeth whitening gel on teeth sensitivity and relief of dry mouth. 

    To qualify for participation, you must be: 

    • 18 years of age or older 
    • Taking a medication that causes dry mouth as a side affect

    You may not be in this study if you: 

    • Are currently using any teeth whitening or desensitizing products such as Sensodyne 
    • Have any conditions that would affect saliva production such as Sjogren’s Syndrome 
    • Are currently participating in any other research studies 

      This is a 1 week, 2 visit study. Qualifying participants that complete all visits will receive a total of $150 in Target gift cards. 

    If you have any questions, or think that you may qualify to participate, please contact: Dr. Mabi Singh (617-636-3931).