Current Clinical Trials and Studies

Are you interested in being a research participant? TUSDM is currently recruiting for the following studies:

Dry Mouth Study

Looking for patients with dry mouth who are 18 years or older and have incipient lesions (newly formed cavities). Participation takes place over six weeks and involves two visits. We will collect and analyze saliva samples, conduct a thorough oral examination and complete ICDAS charting (a cavity detection system). Compensation is $25 at the first visit and $75 at the last visit, totaling $100. Please call Jacob Silberstein at (617) 636-2147 if you are interested in participating.

Sensitivity Study

We are looking for volunteers for a study focusing on sensitivity and gingival recession. Participants must be at least 18 years old, have at least 8 natural front teeth, be free of gum disease and be available for 3 visits within 8 days and then a final visit after 5 weeks. Participants can receive up to $125 in gift cards for completing the study visits. To schedule a screening appointment, please call 617-636-3931.

Wisdom Tooth & Dental Dressing Research Study

We are seeking volunteers for a study testing the use of a dental dressing material in reducing post-surgical complications following the removal of wisdom teeth. Participants must be between 18 and 30 years old, require the surgical removal of your top two or bottom two wisdom teeth and be able to physically tolerate conventional surgical procedures. You may not participate in this study if you have an allergy to seafood, you have an allergy to drugs used in routine oral surgery, or if you are currently pregnant. Compensation for patients completing the study is a total of $30 in gift cards. For more information, please contact Paula O’Brien [ (617) 636-2484] or Dr. Ghassan Darwish [ (617) 636-0806]. All study appointments will take place in the Oral and Maxillofacial Surgery clinic at TUSDM.

Wisdom Tooth Removal & Pain Study

We are seeking volunteers for a study testing a pain reduction patch for wisdom teeth removal. We would like to see if application of the patches on your cheeks reduces pain after teeth are extracted. Participants must be 18-30 years old, medically healthy, able to attend three study visits, and planning to have all four wisdom teeth extracted (wisdom teeth must be fully or partially impacted). Participants who qualify and complete the study will receive up to $125 in gift cards for their participation. For more information, please contact Dr. William Gilmore ( or Cassandra O’Connell (; 617-636-0490)

Wisdom Tooth Removal & Preemptive Administration of Pain Killers

This research study will compare the effectiveness of a single dose of intravenous (IV) ibuprofen or IV acetaminophen when given 30 minutes prior to surgery in reducing post-operative pain.  You will be observed for one and a half hours after the surgical procedure and will receive post-surgery care as needed. Participants must be at least 18 years old, in good general health and need two or more wisdom teeth third molars extracted under general anesthesia. You will receive up to $50 in gift cards after successful completion of the study. In addition, parking on the day of your surgery will be paid by parking vouchers.  Individuals, or their insurance company, will be responsible for covering all surgical costs.

The study involves three parts:

  1. A screening appointment that will take approximately 30 minutes,
  2. Pre-surgery administration of ibuprofen or acetaminophen and post-operative observation, and
  3. Completion of pain diary

If you would like to learn more about the study, please contact Dr. Archana Viswanath at (617) 636-3578 or by email at

Interested participants should call Jacob Silberstein at
(617) 636-2147

If you have a current or upcoming clinical trial that you would like to advertise for, please contact Jacob to discuss posting options.

For more information about becoming a research subject, click here.

Actually, I just want to become a regular patient. >>