Current Clinical Trials and Studies

Are you interested in being a research participant? TUSDM is currently recruiting for the following studies:

Dental Research Study Seeking Volunteers

Description: The Periodontology Department of Tufts University School of Dental Medicine is conducting research on the systemic immune response in subjects with and without periodontitis.

We are seeking volunteers who are between 40-70 years old and speak English and who have not received periodontal treatment in the past 3 months. Participants must be willing to attend 1-2 visits for this study (1 visit for patients without periodontitis and 2 visits for patients with periodontitis, 1 pre- and 1 post-treatment).

Subjects participating in the study will receive a $25 gift card to CVS after each completed study visit (1 visit for healthy volunteers, 2 visits for patients with periodontitis).

If you have any questions or if you think you may qualify to participate, please contact:

Dr. Evangelos Papathanasiou
Contact Phone:  (617) 636-3887

Dental Cavities Research Study Seeking Volunteers

We are seeking volunteers for a study comparing two different materials that are used to fill cavities.

To qualify, you must:

  • Be at least 18 years of age
  • Have two back teeth with cavities in need of fillings
  • Must not have had treatment on those teeth in the past 12 months

If you qualify for the study, one of your teeth will be randomly selected to receive a filling with one material, and your other tooth will be randomly selected to receive a filling with a second material. Both materials are approved by the FDA to be used to fill cavities.

There are a total of 5 visits over a 2-year period. Qualifying participants will receive the two fillings free of charge, and a total of $245 in gift cards if you complete all study visits. All study visits take place at Tufts University School of Dental Medicine.

If you think you may qualify, please contact Courtney Thurell at or 617-636-3865 for more information.

Dental Research Study: Recession

Think You’ve Got recession?

The Periodontology Department is conducting research regarding treatment for gum recession.

  • Are you over 18 years old?
  • Have you been told that you have gingival recessions?
  • 8 study visits; over an approximately 13 month period;
  • 50% of the surgical costs will be covered;
  • Upon completing the study, you will receive up to $60 in CVS gift cards as compensation.

If you have any questions or if you think you may qualify to participate, please contact:

Dr. Kai Chyuan Lei
(415) 683-6038

Dental Research Study: Bone Volume Gain

We are looking volunteers for a clinical research study focusing on bone volume gain after a specific bone regeneration surgery. You may qualify to participate if you are a current TUSDM clinic patient who is:

    • At least 18 years old
    • A non-smoker
    • Have been diagnosed with lateral ridge deficiencies
    • And require treatment by lateral bone augmentation surgery, implant placement and implant supported prosthesis

Qualifying participants will receive a 50% discount on the lateral bone augmentation surgery. Participants and/or their insurance will be responsible for one half of the bone regeneration procedure fee and the full fee for implant placement.

If you have any questions or if you think you may qualify to participate, please contact:

Dr. Angela Wang

Dentinal Hypersensitivity Study

We are seeking volunteers for a study on the efficacy of three cavity prevention products in helping to minimize dentinal hypersensitivity.

Participants must:

    • Be at least 18 years of age
    • Have at least one tooth with an exposed root surface and/or exposed dentin
    • Have no adjacent teeth with sensitivity

You may not participate in this study if :

    • You have any pain disorders
    • You have a chronic medical condition that requires the regular use of pain or anti-inflammatory medications
    • You have used a desensitizing dentifrice within the past four weeks
    • You have received an antihypersensitivity treatment (varnish or precipitating solution) within the past four weeks
    • You are undergoing active orthodontic treatment.
    • You are pregnant or lactating
    • You have a milk allergy
    • You are on kidney dialysis

Compensation for participating in the study is up to $100 in gift cards.

If you have any questions or if you think you may qualify to participate, please contact:

Dr. Britta Magnuson

All study appointments will take place in the periodontology clinic at TUSDM .

Wisdom Tooth Removal & Preemptive Administration of Pain Killers

This research study will compare the effectiveness of a single dose of intravenous (IV) ibuprofen or IV acetaminophen when given 30 minutes prior to surgery in reducing post-operative pain.  You will be observed for one and a half hours after the surgical procedure and will receive post-surgery care as needed. Participants must be at least 18 years old, in good general health and need two or more wisdom teeth third molars extracted under general anesthesia. You will receive up to $50 in gift cards after successful completion of the study. In addition, parking on the day of your surgery will be paid by parking vouchers.  Individuals, or their insurance company, will be responsible for covering all surgical costs.

The study involves three parts:

  1. A screening appointment that will take approximately 30 minutes,
  2. Pre-surgery administration of ibuprofen or acetaminophen and post-operative observation, and
  3. Completion of pain diary

If you would like to learn more about the study, please contact Dr. Archana Viswanath at (617) 636-3578 or by email at

Interested participants should call James Kirchmeyer at (617) 636-0490.

If you have a current or upcoming clinical trial that you would like to advertise for, please contact James to discuss posting options.

For more information about becoming a research subject, click here.

Or, click here to become a regular patient at Tufts Dental School ►