Current Clinical Trials and Studies

Are you interested in being a research participant? TUSDM is currently recruiting for the following studies:

Dental Research Study: Bone Volume Gain

We are looking volunteers for a clinical research study focusing on bone volume gain after a specific bone regeneration surgery. You may qualify to participate if you are a current TUSDM clinic patient who is:

    • At least 18 years old
    • A non-smoker
    • Have been diagnosed with lateral ridge deficiencies
    • And require treatment by lateral bone augmentation surgery, implant placement and implant supported prosthesis

Qualifying participants will receive a 50% discount on the lateral bone augmentation surgery. Participants and/or their insurance will be responsible for one half of the bone regeneration procedure fee and the full fee for implant placement.

If you think that you might qualify or to find out more information, Contact Dr. Lorenzo Mordini at 617-292-3433 or Lorenzo.Mordini@tufts.edu

Dental Implants Research Study

We are seeking volunteers for a study looking at three different abutments, which are the pieces that connect a crown to an implant site. We want to compare how each of the abutments look.

To participate in this study you must be:

    • Aged 21 years or older
    • English speaking
    • Medically healthy
    • Able to attend 9 study visits over a two year period
    • In need of an implant supported single tooth restoration in the esthetic zone (teeth at the front of your mouth that can be seen when you smile).

If you qualify and attend study visits, you will receive the implant and surgery for free.  The crown and abutment will be provided for free.  You will receive up to $200 in gift cards.

Please contact Jacinto Cano Peyró if you would like to receive more information about this study: Jacinto.Cano_Peyro@tufts.edu or 617-388-2398

Dentinal Hypersensitivity Study

We are seeking volunteers for a study on the efficacy of three cavity prevention products in helping to minimize dentinal hypersensitivity.

Participants must:

    • Be at least 18 years of age
    • Have at least one tooth with an exposed root surface and/or exposed dentin
    • Have no adjacent teeth with sensitivity

You may not participate in this study if :

    • You have any pain disorders
    • You have a chronic medical condition that requires the regular use of pain or anti-inflammatory medications
    • You have used a desensitizing dentifrice within the past four weeks
    • You have received an antihypersensitivity treatment (varnish or precipitating solution) within the past four weeks
    • You are undergoing active orthodontic treatment.
    • You are pregnant or lactating
    • You have a milk allergy
    • You are on kidney dialysis

Compensation for participating in the study is up to $100 in gift cards.

For more information, please contact Dr. Pamela Maragliano-Muniz at 617-636-3576 Pamela.Maragliano@tufts.edu.

All study appointments will take place in the periodontology clinic at TUSDM .

Dry Mouth Study

Looking for patients with dry mouth who are 18 years or older and have incipient lesions (newly formed cavities). Participation takes place over six weeks and involves two visits. We will collect and analyze saliva samples, conduct a thorough oral examination and complete ICDAS charting (a cavity detection system). Compensation is $25 at the first visit and $75 at the last visit, totaling $100. Please call Jacob Silberstein at (617) 636-2147 if you are interested in participating.

Sensitivity Study

We are looking for volunteers for a study focusing on sensitivity and gingival recession. Participants must be at least 18 years old, have at least 8 natural front teeth, be free of gum disease and be available for 3 visits within 8 days and then a final visit after 5 weeks. Participants can receive up to $125 in gift cards for completing the study visits. To schedule a screening appointment, please call 617-636-3931.

Wisdom Tooth & Dental Dressing Research Study

We are seeking volunteers for a study testing the use of a dental dressing material in reducing post-surgical complications following the removal of wisdom teeth. Participants must be between 18 and 30 years old, require the surgical removal of your top two or bottom two wisdom teeth and be able to physically tolerate conventional surgical procedures. You may not participate in this study if you have an allergy to seafood, you have an allergy to drugs used in routine oral surgery, or if you are currently pregnant. Compensation for patients completing the study is a total of $30 in gift cards. For more information, please contact Paula O’Brien [paula.obrien@tufts.edu (617) 636-2484] or Dr. Ghassan Darwish [ghassan.darwish@tufts.edu (617) 636-0806]. All study appointments will take place in the Oral and Maxillofacial Surgery clinic at TUSDM.

Wisdom Tooth Removal & Pain Study

We are seeking volunteers for a study testing a pain reduction patch for wisdom teeth removal. We would like to see if application of the patches on your cheeks reduces pain after teeth are extracted. Participants must be 18-30 years old, medically healthy, able to attend three study visits, and planning to have all four wisdom teeth extracted (wisdom teeth must be fully or partially impacted). Participants who qualify and complete the study will receive up to $125 in gift cards for their participation. For more information, please contact Dr. William Gilmore (William.Gilmore@tufts.edu) or Cassandra O’Connell (Cassandra.Oconnell@tufts.edu; 617-636-0490)

Wisdom Tooth Removal & Preemptive Administration of Pain Killers

This research study will compare the effectiveness of a single dose of intravenous (IV) ibuprofen or IV acetaminophen when given 30 minutes prior to surgery in reducing post-operative pain.  You will be observed for one and a half hours after the surgical procedure and will receive post-surgery care as needed. Participants must be at least 18 years old, in good general health and need two or more wisdom teeth third molars extracted under general anesthesia. You will receive up to $50 in gift cards after successful completion of the study. In addition, parking on the day of your surgery will be paid by parking vouchers.  Individuals, or their insurance company, will be responsible for covering all surgical costs.

The study involves three parts:

  1. A screening appointment that will take approximately 30 minutes,
  2. Pre-surgery administration of ibuprofen or acetaminophen and post-operative observation, and
  3. Completion of pain diary

If you would like to learn more about the study, please contact Dr. Archana Viswanath at (617) 636-3578 or by email at Archana.Viswanath@tufts.edu.

Interested participants should call Jacob Silberstein at (617) 636-2147.

If you have a current or upcoming clinical trial that you would like to advertise for, please contact Jacob to discuss posting options.

For more information about becoming a research subject, click here.

Or, click here to become a regular patient at Tufts Dental School ►